Suzhou’s first cryogenic electron microscopy (cryo-EM) was unveiled alongside a matching AI dual-engine platform on July 30. Developed by the SIP-UCLA Institute for Technology Advancement in SIP, the platform combines cutting-edge cryo-EM technology with a large amount of medical data to form a biomedicine innovation system spanning fundamental research to clinical applications to accelerate drug discovery and smart diagnostics.

It is worth mentioning that the “Baiyun 4M/16M” TEM camera and cryo-sample preparation instruments in the platform, jointly developed by the institute and SIP-based Blue Jay Imaging, are recognized as domestic alternatives to imported counterparts.

The 200KV cryo-EM, equipped with high-performance probe, enables atomic-resolution imaging to advance studies of drug delivery mechanisms and protein structure analysis. The SBDD (structure-based drug design)/AIDD (AI drug discovery) computing platform optimizes drug target screening and lead compound design, thereby slashing R&D cycle and cost.

This platform marks a breakthrough that China has achieved in integrating micro-probing technology with AI-driven medical treatment. Backed by SIP’s innovation ecosystem, it is poised to accelerate technology commercialization and industrial upgrading in the field of biomedicine, and contribute to global medical progress.

Source: Suzhou Daily, July 31, 2025